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1、8.Thiscellline(A-549)wasdescribedbyD.J.miller,A.J.Pappelis,Mech.AgeingDev.7,417ralysiswereobserved.Whenfreshbrain-Giard,S.A.Aaronson,G.J.Todard,P.Arn-(1978).stemmaterialfromstein,J.H.Kersey,H.Dorsik,andW.P.Parks12.P.M.BemillerandL.H.Lee,ibid.8,amouseth
2、atdied99[J.Natl.CancerInst.51,1417(1973)];M.Lie-417(1978).daysafterinoculationwasinoculatedin-ber,B.Smith,A.Szakal,W.Nelson-Rees,and13.C.K.ChowandA.L.Tappel,Lipids1,518G.A.Todardo[Int.J.Cancer17,62(1976)];and(1972).tracerebrallyintoweanlingmice,theyK.L
3、.Jones,N.S.AndersonIII,andJ.Addison14.C.K.Chow,Nature(London)260,721(1976).developedneurologicalsignsinapproxi-[CancerRes.38,1688(1978)].15.R.E.Kimballetal.,Am.J.Physiol.230,9.thiscellline(MCF-7,estrogen-sensitive)was1425(1976).mately50days.Brainstemma
4、terialob-describedS.Albert,byandH.D.M.Soule,BrennanJ.Vazquez,[J.Natl.A.CancerLong,17.16.0.R.E.S.Selawry,Lee,Semin.ibid.,Oncol.p.259.1,254(1974).tainedfromthesemicewasinoculatedInst.51,1409(1973)]andbyK.B.Horwitz,M.18.Partsofthisreportwerepresentedatthe
5、27thintracerebrallyintonewbornBALB/cE.Kostlow,andW.I.McGuire[Steroids26,AnnualMeetingoftheSocietyforGynecologic785(1975)].Investigation,Denver,20to23March1980(ab-mice,andtheydiedin12days.Insub-10.Humanuterinecarcinosarcomacellsandendo-stracts7and150),a
6、ndatthe73rdAnnualMeet-sequentserialpassagesthetimebetweenmetrialadenocarcinomacellswereobtainedingoftheAirPollutionControlAssociation,frompathologicallyconfirmedgynecologictu-Montreal,24June1980(postersession27).Weinoculationanddeathdecreasedto3to5mors
7、anddevelopedasnewcelllines.Theendo-thankW.Nelson-ReesforhisgiftofA-549cells;days.Wediscoveredduringearlypas-metrialadenocarcinomacelllineisestrogen-theMCF-7cellswereobtainedfromE.M.Jen-sensitive.BothweredescribedbyM.S.Kaosen.WealsothankC.M.Copley,Jr.,H
8、.M.sageattemptsthatthefreezingofbrainandS.C.D.Lee(27thAnnualMeetingoftheCamel,andT.MorganfortheirconstructivematerialfromweanlingandnewbornSocietyforGynecologicInvestigation,Denver,criticismofthemanuscript.Correspondence20to23March1980)
