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1、醋酸鈣及碳酸鈣在維持性血液透析患者高磷血癥治療中的療效觀察卓利(資陽(yáng)市安岳縣人民醫(yī)院腎內(nèi)科資陽(yáng)安岳642350)【摘要】A的：探討醋酸鈣和碳酸鈣治療維持性血液透析患者高磷血癥的臨床療效。方法：選擇60例維持性血液透析合并高磷血癥患者，隨機(jī)分為醋酸鈣組及碳酸鈣組，每組30例，分別給予醋酸鈣及碳酸鈣治療，比較兩組患者治療前后血鈣及血磷水平變化及不良反應(yīng)發(fā)生情況。結(jié)果:兩組患者4周及8周后，血磷水平均較治療前卜降，醋酸鈣組治療第4周及第8周血磷水平低于碳酸鈣組,兩組患者治療4周后血鈣水平較治療前無(wú)明顯變化，治療8周后血鈣水平較治療前
2、升高，碳酸鈣組血鈣水平高于醋酸鈣組，兩組患者治療4周及8周后血淸甲狀旁腺素水平無(wú)明顯變化，兩組間比較無(wú)顯著差異。醋酸鈣組高鈣血癥發(fā)生率為,碳酸鈣組高鈣血癥發(fā)生率為，兩組無(wú)顯著差異。結(jié)論：醋酸鈣治療維持性血液透析患者高磷血癥起效快，降磷效果好，對(duì)血鈣水平影響小，具有較好的臨床效果?！娟P(guān)鍵詞】醋酸鈣；碳酸鈣；高磷血癥；高鈣血癥【中圖分類號(hào)】R45【文獻(xiàn)標(biāo)識(shí)碼】A【文章編號(hào)】2095-1752(2015)17-0179-02Curativeeffectofcalciumacetateandcalciumcarbonateinmain
3、tenancehemodialysisofpatientswithhyperphosphatemiaZhuoLiDepartmentofRenaInternalMedicine,AnyuePeople'sHospitalofZiyangCityAnyue642350[Abstract]ObjectiveToinvestigatethecalciumacetateandcalciumcarbonatetreatmentofmaintenancehemodialysispatientsclinicalcurativeeffecto
4、fhyperphosphatemia.Methods60casesofmaintenancehemodialysispatientswithhyperphosphatemiawereselected,randomlydividedintothegroupofcalciumacetateandcalciumcarbonategroup,30casesineachgroup,weretreatedwithcalciumacetateandcalciumcarbonatetreatment,twogroupswerecompared
5、beforeandaftertreatmentchangesinserumcalciumandphosphoruslevelsandtheincidenceofadversereactions.ResultsThetwogroupsofpatientsfor4weeksand8weekslater,serumphosphoruslevelswerelowerthanthatbeforetreatment,calciumacetategroupforfourthweeksand8weeksofbloodphosphoruslev
6、elislowerthanthecalciumcarbonategroup,treatmentgrouptwopatientsafter4weeksofbloodcalciumlevelsbeforetreatmenthadnoobviouschange,after8weeksoftreatment,serumcalciumlevelswereincreasedcomparedwithbeforetreatment,calciumcarbonategroupishigherthanthelevelofcalciumincalc
7、iumacetategroup,treatmentgrouptwopatientshadnoobviouschangein4and8weeksaftertheserumparathyroidhormonelevels,andthereisnosignificantdifferencebetweenthetwogroups.Theincidenceofhypercalcemia,calciumacetategroup,calciumcarbonategrouptheincidenceofhypercalcemia,nosigni
8、ficantdifferencebetweenthetwogroups.ConclusionCalciumacetateintreatinghemodialysispatientswithhyperphosphatemiarapidonset,phosphorusreduct
